These teams are two of the bookies favourites to win the Stanley Cup this season, so this is a game for one of them to back up those credentials with a win over a potential title rival.
The Maple Leafs had won two of their opening three games prior to facing the St. Louis Blues on Monday night which saw them go down to a 2-3 defeat with Alex Pietrangelo scoring the winning goal for the Blues in the third period.
The Lightning started their season with a 5-2 win on home-ice against the Florida Panthers last Thursday, but then lost 4-3 in the reverse game in Florida on Saturday night.
Last season the Lightning tied the NHL record with 62 wins, but they were unable to maintain the momentum in the playoffs as they failed to win a single game in losing 4-0 to the Columbus Blue Jackets.
Toronto Maple Leafs vs Tampa Bay Lightning Betting Lines & Prediction
Home-ice advantage could just give the Maple Leafs the edge here when it comes to NHL bet predictions for this game and the tip is for Toronto to win. With both teams starting the season by scoring and allowing plenty of goals, this could also potentially be a high-scoring game.
In the Moneyline betting market the online bookies can barely split these two teams with the Toronto Maple Leafs available to back at -112.36 (1.89) with Sport Interaction and the best betting line on Tampa Bay Lightning on offer at -105.26 (1.95) with bet365.