The teams met each other just once last season, with San Jose winning 2-1 in Canada thanks to the two goals from veteran striker Chris Wondolowski. Richie Laryea had given Toronto the lead.
Eventually the Earthquakes finished one place and four points short of qualifying from the Western Conference for the MLS play-offs last season, while the Reds went all the way to the MLS Cup Final before losing 3-1 to the Seattle Sounders.
The biggest addition to the San Jose squad over the close season is that of Mexican central defender Oswaldo Alanis, who is reunited with his former manager at Guadalajara, Matias Almeyda.
For Toronto, the main recruit in the close season was the Argentinean midfielder Pablo Piatti from Espanyol, although he will miss the trip to San Jose with a hamstring injury. Also missing for the Reds is Michael Bradley following ankle surgery.
San Jose Earthquakes vs Toronto FC Betting Lines & MLS Prediction
The opening games of a new season in any sport are often difficult to assess from a betting perspective, but Toronto will again be expected to achieve more than San Jose over the course of the season, so they look a decent tip to come away with a draw in our MLS betting predictions for this game.
In the Match Result odds, the best betting line on San Jose is at +101 (2.01) with Sports Interaction, the draw is available at odds of +270 (3.70) with Sports Interaction and Toronto can be backed at +250 (3.50) with bet365.